describe the process of DNA replication and explain its significance
perform a first-hand investigation or process information from secondary sources to develop a simple model for polypeptide synthesis
analyse information from secondary sources to outline the evidence that led to Beadle and Tatum’s ‘one gene – one protein’ hypothesis and to explain why this was altered to the ‘one gene – one polypeptide’ hypothesis process information to construct a flow chart that shows that changes in DNA sequences can result in changes in cell activity
process and analyse information from secondary sources to explain a modern example of ‘natural’ selection
process information from secondary sources to describe and analyse the relative importance of the work of: – James Watson – Francis Crick – Rosalind Franklin – Maurice Wilkins in determining the structure of DNA and the impact of the quality of collaboration and communication on their scientific research outline, using a simple model, the process by which DNA controls the production of polypeptides
explain the relationship between proteins and polypeptides
explain how mutations in DNA may lead to the generation of new alleles
discuss evidence for the mutagenic nature of radiation
explain how an understanding of the source of variation in organisms has provided support for Darwin’s theory of evolution by natural selection
describe the concept of punctuated equilibrium in evolution and how it differs from the gradual process proposed by Darwin
