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Science 12 - Biology: 3. Chromosomal structure provides the key to inheritance

Students learn

  •  outline the roles of Sutton and Boveri in identifying the importance of chromosomes
  • process information from secondary sources to construct a model that demonstrates meiosis and the processes of crossing over, segregation of chromosomes and the production of haploid gametes
  • solve problems involving codominance and sex linkage
  •  identify data sources and perform a first-hand investigation to demonstrate the effect of environment on phenotype
  • describe the chemical nature of chromosomes and genes
  • identify that DNA is a double-stranded molecule twisted into a helix with each strand comprised of a sugar-phosphate backbone and attached bases – adenine (A), thymine (T), cytosine (C) and guanine (G) – connected to a complementary strand by pairing the bases, A-T and G-C
  • explain the relationship between the structure and behaviour of chromosomes during meiosis and the inheritance of genes
  • explain the role of gamete formation and sexual reproduction in variability of offspring
  • describe the inheritance of sex-linked genes, and alleles that exhibit co-dominance and explain why these do not produce simple Mendelian ratios
  • describe the work of Morgan that led to the understanding of sex linkage
  • explain the relationship between homozygous and heterozygous genotypes and the resulting phenotypes in examples of co-dominance
  • outline ways in which the environment may affect the expression of a gene in an individual